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Sin3A recruits Tet1 to the PAH1 domain via a highly conserved Sin3-Interaction Domain
The Sin3A complex acts as a transcriptional hub, integrating the function of diverse transcription factors with histone modifying enzymes, notably, histone deacetylases (HDAC) 1 and 2. The Sin3A protein sits at the centre of the complex, mediating multiple simultaneous protein-protein interactions v...
Autores principales: | Chandru, Aditya, Bate, Neil, Vuister, Geerten W., Cowley, Shaun M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168491/ https://www.ncbi.nlm.nih.gov/pubmed/30279502 http://dx.doi.org/10.1038/s41598-018-32942-w |
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