Drug screening of biopsy-derived spheroids using a self-generated microfluidic concentration gradient

Performing drug screening of tissue derived from cancer patient biopsies using physiologically relevant 3D tumour models presents challenges due to the limited amount of available cell material. Here, we present a microfluidic platform that enables drug screening of cancer cell-enriched multicellula...

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Detalles Bibliográficos
Autores principales: Mulholland, Theresa, McAllister, Milly, Patek, Samantha, Flint, David, Underwood, Mark, Sim, Alexander, Edwards, Joanne, Zagnoni, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168499/
https://www.ncbi.nlm.nih.gov/pubmed/30279484
http://dx.doi.org/10.1038/s41598-018-33055-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168499/
https://www.ncbi.nlm.nih.gov/pubmed/30279484
http://dx.doi.org/10.1038/s41598-018-33055-0

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