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Dereplication of microbial metabolites through database search of mass spectra

Natural products have traditionally been rich sources for drug discovery. In order to clear the road toward the discovery of unknown natural products, biologists need dereplication strategies that identify known ones. Here we report DEREPLICATOR+, an algorithm that improves on the previous approache...

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Detalles Bibliográficos
Autores principales: Mohimani, Hosein, Gurevich, Alexey, Shlemov, Alexander, Mikheenko, Alla, Korobeynikov, Anton, Cao, Liu, Shcherbin, Egor, Nothias, Louis-Felix, Dorrestein, Pieter C., Pevzner, Pavel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168521/
https://www.ncbi.nlm.nih.gov/pubmed/30279420
http://dx.doi.org/10.1038/s41467-018-06082-8