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A Non-Targeted LC-MS Profiling Reveals Elevated Levels of Carnitine Precursors and Trimethylated Compounds in the Cord Plasma of Pre-Eclamptic Infants

Preeclampsia (PE) is a complex pregnancy disorder. It is not extensively known how the metabolic alterations of PE women contribute to the metabolism of newborn. We applied liquid chromatography-mass spectrometry (LC-MS) based non-targeted metabolomics to determine whether the metabolic profile of p...

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Detalles Bibliográficos
Autores principales: Jääskeläinen, Tiina, Kärkkäinen, Olli, Jokkala, Jenna, Litonius, Kaisa, Heinonen, Seppo, Auriola, Seppo, Lehtonen, Marko, Hanhineva, Kati, Laivuori, Hannele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168522/
https://www.ncbi.nlm.nih.gov/pubmed/30279541
http://dx.doi.org/10.1038/s41598-018-32804-5