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In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies

The black mamba (Dendroaspis polylepis) is one of the most feared snake species of the African savanna. It has a potent, fast-acting neurotoxic venom comprised of dendrotoxins and α-neurotoxins associated with high fatality in untreated victims. Current antivenoms are both scarce on the African cont...

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Detalles Bibliográficos
Autores principales: Laustsen, Andreas H., Karatt-Vellatt, Aneesh, Masters, Edward W., Arias, Ana Silvia, Pus, Urska, Knudsen, Cecilie, Oscoz, Saioa, Slavny, Peter, Griffiths, Daniel T., Luther, Alice M., Leah, Rachael A., Lindholm, Majken, Lomonte, Bruno, Gutiérrez, José María, McCafferty, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168529/
https://www.ncbi.nlm.nih.gov/pubmed/30279409
http://dx.doi.org/10.1038/s41467-018-06086-4