The Chemokine CCL3 Regulates Myeloid Differentiation and Hematopoietic Stem Cell Numbers

The chemokine CCL3 is frequently overexpressed in malignancies and overexpression leads to microenvironmental dysfunction. In murine models of chronic myelogenous leukemia (CML), CCL3 is critical for the maintenance of a leukemia stem cell population, and leukemia progression. With CCL3 implicated a...

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Detalles Bibliográficos
Autores principales: Staversky, Rhonda J., Byun, Daniel K., Georger, Mary A., Zaffuto, Brandon J., Goodman, Alexandra, Becker, Michael W., Calvi, Laura M., Frisch, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168534/
https://www.ncbi.nlm.nih.gov/pubmed/30279500
http://dx.doi.org/10.1038/s41598-018-32978-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168534/
https://www.ncbi.nlm.nih.gov/pubmed/30279500
http://dx.doi.org/10.1038/s41598-018-32978-y

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