Cargando…

How phosphorylation influences E1 subunit pyruvate dehydrogenase: A computational study

Pyruvate (PYR) dehydrogenase complex (PDC) is an enzymatic system that plays a crucial role in cellular metabolism as it controls the entry of carbon into the Krebs cycle. From a structural point of view, PDC is formed by three different subunits (E1, E2 and E3) capable of catalyzing the three react...

Descripción completa

Detalles Bibliográficos
Autores principales: Sgrignani, Jacopo, Chen, JingJing, Alimonti, Andrea, Cavalli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168537/
https://www.ncbi.nlm.nih.gov/pubmed/30279533
http://dx.doi.org/10.1038/s41598-018-33048-z