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How phosphorylation influences E1 subunit pyruvate dehydrogenase: A computational study
Pyruvate (PYR) dehydrogenase complex (PDC) is an enzymatic system that plays a crucial role in cellular metabolism as it controls the entry of carbon into the Krebs cycle. From a structural point of view, PDC is formed by three different subunits (E1, E2 and E3) capable of catalyzing the three react...
Autores principales: | Sgrignani, Jacopo, Chen, JingJing, Alimonti, Andrea, Cavalli, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168537/ https://www.ncbi.nlm.nih.gov/pubmed/30279533 http://dx.doi.org/10.1038/s41598-018-33048-z |
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