Mesenchymal stem cells are attracted to latent HIV-1-infected cells and enable virus reactivation via a non-canonical PI3K-NFκB signaling pathway

Persistence of latent HIV-1 in macrophages (MACs) and T-helper lymphocytes (THLs) remain a major therapeutic challenge. Currently available latency reversing agents (LRAs) are not very effective in vivo. Therefore, understanding of physiologic mechanisms that dictate HIV-1 latency/reactivation in re...

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Detalles Bibliográficos
Autores principales: Chandra, Partha K., Gerlach, Samantha L., Wu, Chengxiang, Khurana, Namrata, Swientoniewski, Lauren T., Abdel-Mageed, Asim B., Li, Jian, Braun, Stephen E., Mondal, Debasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168583/
https://www.ncbi.nlm.nih.gov/pubmed/30279437
http://dx.doi.org/10.1038/s41598-018-32657-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168583/
https://www.ncbi.nlm.nih.gov/pubmed/30279437
http://dx.doi.org/10.1038/s41598-018-32657-y

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