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Permissiveness to form pluripotent stem cells may be an evolutionarily derived characteristic in Mus musculus

Mus musculus is the only known species from which embryonic stem cells (ESC) can be isolated under conditions requiring only leukemia inhibitory factor (LIF). Other species are non-permissive in LIF media, and form developmentally primed epiblast stem cells (EpiSC) similar to cells derived from post...

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Detalles Bibliográficos
Autores principales: Garbutt, Tiffany A., Konneker, Thomas I., Konganti, Kranti, Hillhouse, Andrew E., Swift-Haire, Francis, Jones, Alexis, Phelps, Drake, Aylor, David L., Threadgill, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168588/
https://www.ncbi.nlm.nih.gov/pubmed/30279419
http://dx.doi.org/10.1038/s41598-018-32116-8