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Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape
Regulation of transcription, replication, and cell division relies on differential protein binding to DNA and chromatin, yet it is unclear which regulatory components remain bound to compacted mitotic chromosomes. By utilizing the buoyant density of DNA–protein complexes after cross-linking, we here...
Autores principales: | Ginno, Paul Adrian, Burger, Lukas, Seebacher, Jan, Iesmantavicius, Vytautas, Schübeler, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168604/ https://www.ncbi.nlm.nih.gov/pubmed/30279501 http://dx.doi.org/10.1038/s41467-018-06007-5 |
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