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Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ(9)-THC

Recreational use of marijuana is associated with few adverse effects, but abuse of synthetic cannabinoids (SCBs) can result in anxiety, psychosis, chest pain, seizures and death. To potentially explain higher toxicity associated with SCB use, we hypothesized that AB-PINACA, a common second generatio...

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Detalles Bibliográficos
Autores principales: Hutchison, Rachel D., Ford, Benjamin M., Franks, Lirit N., Wilson, Catheryn D., Yarbrough, Azure L., Fujiwara, Ryoichi, Su, Mark K., Fernandez, Denise, James, Laura P., Moran, Jeffery H., Patton, Amy L., Fantegrossi, William E., Radominska-Pandya, Anna, Prather, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168621/
https://www.ncbi.nlm.nih.gov/pubmed/30319418
http://dx.doi.org/10.3389/fphar.2018.01084