Neuropsychiatric Systemic Lupus Erythematosus Is Dependent on Sphingosine-1-Phosphate Signaling

About 40% of patients with systemic lupus erythematosus experience diffuse neuropsychiatric manifestations, including impaired cognition and depression. Although the pathogenesis of diffuse neuropsychiatric SLE (NPSLE) is not fully understood, loss of brain barrier integrity, autoreactive antibodies...

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Detalles Bibliográficos
Autores principales: Mike, Elise V., Makinde, Hadijat M., Der, Evan, Stock, Ariel, Gulinello, Maria, Gadhvi, Gaurav T., Winter, Deborah R., Cuda, Carla M., Putterman, Chaim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168636/
https://www.ncbi.nlm.nih.gov/pubmed/30319641
http://dx.doi.org/10.3389/fimmu.2018.02189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168636/
https://www.ncbi.nlm.nih.gov/pubmed/30319641
http://dx.doi.org/10.3389/fimmu.2018.02189

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