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The amino‐terminal domain of Mycobacterium tuberculosis ClpB protein plays a crucial role in its substrate disaggregation activity

Mycobacterium tuberculosis (Mtb) is known to persist in extremely hostile environments within host macrophages. The ability to withstand such proteotoxic stress comes from its highly conserved molecular chaperone machinery. ClpB, a unique member of the AAA+ family of chaperones, is responsible for r...

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Detalles Bibliográficos
Autores principales: Tripathi, Prajna, Parijat, Priyanka, Patel, Virendra Kumar, Batra, Janendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168691/
https://www.ncbi.nlm.nih.gov/pubmed/30338218
http://dx.doi.org/10.1002/2211-5463.12509