Rosiglitazone suppresses RANKL‐induced NFATc1 autoamplification by disrupting the physical interaction between NFATc1 and PPARγ

Receptor activator of nuclear factor‐κB ligand (RANKL) is required for initiation of osteoclastogenesis, with the signaling pathway including the NF‐kB, c‐Fos, and nuclear factor of activated T cells, cytoplasmic 1 (NFATc1) transcription factors. Because NFATc1 expression is autoamplified, we invest...

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Detalles Bibliográficos
Autores principales: Park, Kyeong‐Lok, Oh, Da‐Gyo, Kim, Young‐Ok, Song, Kyeong‐Seob, Ahn, Do‐Whan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168694/
https://www.ncbi.nlm.nih.gov/pubmed/30338210
http://dx.doi.org/10.1002/2211-5463.12513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168694/
https://www.ncbi.nlm.nih.gov/pubmed/30338210
http://dx.doi.org/10.1002/2211-5463.12513

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