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Rosiglitazone suppresses RANKL‐induced NFATc1 autoamplification by disrupting the physical interaction between NFATc1 and PPARγ
Receptor activator of nuclear factor‐κB ligand (RANKL) is required for initiation of osteoclastogenesis, with the signaling pathway including the NF‐kB, c‐Fos, and nuclear factor of activated T cells, cytoplasmic 1 (NFATc1) transcription factors. Because NFATc1 expression is autoamplified, we invest...
Autores principales: | Park, Kyeong‐Lok, Oh, Da‐Gyo, Kim, Young‐Ok, Song, Kyeong‐Seob, Ahn, Do‐Whan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168694/ https://www.ncbi.nlm.nih.gov/pubmed/30338210 http://dx.doi.org/10.1002/2211-5463.12513 |
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