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The reduction in FOXA2 activity during lung development in fetuses from diabetic rat mothers is reversed by Akt inhibition

Hyperglycemia during pregnancy is associated with fetal lung development disorders and surfactant protein (SP) deficiency. Here, we examined the role of FOXA2 and Akt signaling in fetal lung development during diabetic pregnancy. Sprague‐Dawley rats were injected with streptozocin (STZ) during pregn...

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Detalles Bibliográficos
Autores principales: Zhang, Qingmiao, Chai, Xinqun, Deng, Feitao, Ouyang, Weixiang, Song, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168696/
https://www.ncbi.nlm.nih.gov/pubmed/30338211
http://dx.doi.org/10.1002/2211-5463.12517