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A Member of the Ferlin Calcium Sensor Family Is Essential for Toxoplasma gondii Rhoptry Secretion

Invasion of host cells by apicomplexan parasites such as Toxoplasma gondii is critical for their infectivity and pathogenesis. In Toxoplasma, secretion of essential egress, motility, and invasion-related proteins from microneme organelles is regulated by oscillations of intracellular Ca(2+). Later s...

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Detalles Bibliográficos
Autores principales: Coleman, Bradley I., Saha, Sudeshna, Sato, Seiko, Engelberg, Klemens, Ferguson, David J. P., Coppens, Isabelle, Lodoen, Melissa B., Gubbels, Marc-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168857/
https://www.ncbi.nlm.nih.gov/pubmed/30279285
http://dx.doi.org/10.1128/mBio.01510-18