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Dual Role of a Viral Polymerase in Viral Genome Replication and Particle Self-Assembly

Double-stranded RNA (dsRNA) viruses package several RNA-dependent RNA polymerases (RdRp) together with their dsRNA genome into an icosahedral protein capsid known as the polymerase complex. This structure is highly conserved among dsRNA viruses but is not found in any other virus group. RdRp subunit...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoyu, Ilca, Serban L., Huiskonen, Juha T., Poranen, Minna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168860/
https://www.ncbi.nlm.nih.gov/pubmed/30279282
http://dx.doi.org/10.1128/mBio.01242-18