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Treatment of pustular psoriasis with anakinra: a statistical analysis plan for stage 1 of an adaptive two-staged randomised placebo-controlled trial

BACKGROUND: Palmoplantar pustulosis (PPP) is a rare, chronic inflammatory skin disease. It is known to affect quality of life at a level comparable to that from major medical and psychiatric illness, yet current treatment options are remarkably limited. Recent evidence however suggests that interleu...

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Detalles Bibliográficos
Autores principales: Cro, Suzie, Smith, Catherine, Wilson, Rosemary, Cornelius, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169096/
https://www.ncbi.nlm.nih.gov/pubmed/30285894
http://dx.doi.org/10.1186/s13063-018-2914-y