Activation of podocyte Notch mediates early Wt1 glomerulopathy

The Wilms' tumor suppressor gene, WT1, encodes a zinc finger protein that regulates podocyte development and is highly expressed in mature podocytes. Mutations in the WT1 gene are associated with the development of renal failure due to the formation of scar tissue within glomeruli, the mechanis...

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Detalles Bibliográficos
Autores principales: Asfahani, Rowan I., Tahoun, Mona M., Miller-Hodges, Eve V., Bellerby, Jack, Virasami, Alex K., Sampson, Robert D., Moulding, Dale, Sebire, Neil J., Hohenstein, Peter, Scambler, Peter J., Waters, Aoife M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169130/
https://www.ncbi.nlm.nih.gov/pubmed/29398135
http://dx.doi.org/10.1016/j.kint.2017.11.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169130/
https://www.ncbi.nlm.nih.gov/pubmed/29398135
http://dx.doi.org/10.1016/j.kint.2017.11.014

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