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Simultaneous Determination of Columbianadin and Its Metabolite Columbianetin in Rat Plasma by LC-MS/MS: Application to Pharmacokinetics of Columbianadin after Oral Administration

Columbianadin and its metabolite columbianetin exhibited the anti-inflammatory, analgesic, calcium channel blocking and antitumor activities. To compare the differences between pharmacokinetics of columbianadin and its metabolite columbianetin after oral administration of pure columbianadin and Ange...

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Detalles Bibliográficos
Autores principales: Li, Jin, Li, Zhen, Luo, Qian, Wang, Chun-Peng, He, Jun, Pang, Xiaoli, Teye Azietaku, John, Chang, Yan-xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169240/
https://www.ncbi.nlm.nih.gov/pubmed/30327682
http://dx.doi.org/10.1155/2018/8568303