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Simultaneous Determination of Columbianadin and Its Metabolite Columbianetin in Rat Plasma by LC-MS/MS: Application to Pharmacokinetics of Columbianadin after Oral Administration
Columbianadin and its metabolite columbianetin exhibited the anti-inflammatory, analgesic, calcium channel blocking and antitumor activities. To compare the differences between pharmacokinetics of columbianadin and its metabolite columbianetin after oral administration of pure columbianadin and Ange...
Autores principales: | Li, Jin, Li, Zhen, Luo, Qian, Wang, Chun-Peng, He, Jun, Pang, Xiaoli, Teye Azietaku, John, Chang, Yan-xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169240/ https://www.ncbi.nlm.nih.gov/pubmed/30327682 http://dx.doi.org/10.1155/2018/8568303 |
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