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Intermittent administration of a leucine-deprived diet is able to intervene in type 2 diabetes in db/db mice

Continuous deficiency of leucine, a member of branched chain amino acids, is able to reduce obesity and improve insulin sensitivity in mice. Intermittent fasting has been shown to be effective in intervention of metabolic disorders including diabetes. However, it is unknown whether intermittent leuc...

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Detalles Bibliográficos
Autores principales: Wei, Siying, Zhao, Jingyu, Wang, Shuo, Huang, Meiqin, Wang, Yining, Chen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169254/
https://www.ncbi.nlm.nih.gov/pubmed/30294696
http://dx.doi.org/10.1016/j.heliyon.2018.e00830