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PAI-1 Exacerbates White Adipose Tissue Dysfunction and Metabolic Dysregulation in High Fat Diet-Induced Obesity

Background: Plasminogen activator inhibitor (PAI)-1 levels and activity are known to increase during metabolic syndrome and obesity. In addition, previous studies have implicated PAI-1 in adipose tissue (AT) expansion while also contributing to insulin resistance. As inflammation is also known to oc...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Chen, Liyuan, Liu, Zheran, Liu, Yaofang, Luo, Mao, Chen, Ni, Deng, Xin, Luo, Yulin, He, Jing, Zhang, Liping, Hill, Michael A., Li, Rong, Wu, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169321/
https://www.ncbi.nlm.nih.gov/pubmed/30319420
http://dx.doi.org/10.3389/fphar.2018.01087