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PAI-1 Exacerbates White Adipose Tissue Dysfunction and Metabolic Dysregulation in High Fat Diet-Induced Obesity
Background: Plasminogen activator inhibitor (PAI)-1 levels and activity are known to increase during metabolic syndrome and obesity. In addition, previous studies have implicated PAI-1 in adipose tissue (AT) expansion while also contributing to insulin resistance. As inflammation is also known to oc...
Autores principales: | Wang, Lin, Chen, Liyuan, Liu, Zheran, Liu, Yaofang, Luo, Mao, Chen, Ni, Deng, Xin, Luo, Yulin, He, Jing, Zhang, Liping, Hill, Michael A., Li, Rong, Wu, Jianbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169321/ https://www.ncbi.nlm.nih.gov/pubmed/30319420 http://dx.doi.org/10.3389/fphar.2018.01087 |
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