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Functional Interactions Between rsks-1/S6K, glp-1/Notch, and Regulators of Caenorhabditis elegans Fertility and Germline Stem Cell Maintenance

The proper accumulation and maintenance of stem cells is critical for organ development and homeostasis. The Notch signaling pathway maintains stem cells in diverse organisms and organ systems. In Caenorhabditis elegans, GLP-1/Notch activity prevents germline stem cell (GSC) differentiation. Other s...

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Detalles Bibliográficos
Autores principales: Roy, Debasmita, Kahler, David J., Yun, Chi, Hubbard, E. Jane Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169383/
https://www.ncbi.nlm.nih.gov/pubmed/30126834
http://dx.doi.org/10.1534/g3.118.200511