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Imputation-Aware Tag SNP Selection To Improve Power for Large-Scale, Multi-ethnic Association Studies

The emergence of very large cohorts in genomic research has facilitated a focus on genotype-imputation strategies to power rare variant association. These strategies have benefited from improvements in imputation methods and association tests, however little attention has been paid to ways in which...

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Detalles Bibliográficos
Autores principales: Wojcik, Genevieve L., Fuchsberger, Christian, Taliun, Daniel, Welch, Ryan, Martin, Alicia R, Shringarpure, Suyash, Carlson, Christopher S., Abecasis, Goncalo, Kang, Hyun Min, Boehnke, Michael, Bustamante, Carlos D., Gignoux, Christopher R., Kenny, Eimear E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169386/
https://www.ncbi.nlm.nih.gov/pubmed/30131328
http://dx.doi.org/10.1534/g3.118.200502