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APOBEC3 Mediates Resistance to Oncolytic Viral Therapy

Tumor cells frequently evade applied therapies through the accumulation of genomic mutations and rapid evolution. In the case of oncolytic virotherapy, understanding the mechanisms by which cancer cells develop resistance to infection and lysis is critical to the development of more effective viral-...

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Detalles Bibliográficos
Autores principales: Huff, Amanda L., Wongthida, Phonphimon, Kottke, Timothy, Thompson, Jill M., Driscoll, Christopher B., Schuelke, Matthew, Shim, Kevin G., Harris, Reuben S., Molan, Amy, Pulido, Jose S., Selby, Peter J., Harrington, Kevin J., Melcher, Alan, Evgin, Laura, Vile, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169432/
https://www.ncbi.nlm.nih.gov/pubmed/30294666
http://dx.doi.org/10.1016/j.omto.2018.08.003