Combination with SGT-53 overcomes tumor resistance to a checkpoint inhibitor

The tumor suppressor p53 responds to genotoxic and oncogenic stresses by inducing cell cycle arrest and apoptosis. Recent studies suggest that p53 also participates in the regulation of cellular immune responses. Here, we have investigated the potential of p53 gene therapy to augment immune checkpoi...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Soo, Harford, Joe B., Moghe, Manish, Rait, Antonina, Chang, Esther H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169574/
https://www.ncbi.nlm.nih.gov/pubmed/30288347
http://dx.doi.org/10.1080/2162402X.2018.1484982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169574/
https://www.ncbi.nlm.nih.gov/pubmed/30288347
http://dx.doi.org/10.1080/2162402X.2018.1484982

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