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Recurrent aseptic meningitis with PIGT mutations: a novel pathogenesis of recurrent meningitis successfully treated by eculizumab

We report the case of a patient with PIGT mutations who experienced recurrent aseptic meningitis 121 times over 16 years before developing paroxysmal nocturnal haemoglobinuria (PNH). Each episode was preceded by urticaria and arthralgia. After developing PNH, haemolysis occurred prior to meningitis....

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Detalles Bibliográficos
Autores principales: Kawamoto, Michi, Murakami, Yoshiko, Kinoshita, Taroh, Kohara, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169622/
https://www.ncbi.nlm.nih.gov/pubmed/30262533
http://dx.doi.org/10.1136/bcr-2018-225910