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Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals
Addiction has been proposed as a ‘reward deficient’ state, which is compensated for with substance use. There is growing evidence of dysregulation in the opioid system, which plays a key role in reward, underpinning addiction. Low levels of endogenous opioids are implicated in vulnerability for deve...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169731/ https://www.ncbi.nlm.nih.gov/pubmed/29942043 http://dx.doi.org/10.1038/s41380-018-0107-4 |