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Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals

Addiction has been proposed as a ‘reward deficient’ state, which is compensated for with substance use. There is growing evidence of dysregulation in the opioid system, which plays a key role in reward, underpinning addiction. Low levels of endogenous opioids are implicated in vulnerability for deve...

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Detalles Bibliográficos
Autores principales: Turton, Samuel, Myers, James FM, Mick, Inge, Colasanti, Alessandro, Venkataraman, Ashwin, Durant, Claire, Waldman, Adam, Brailsford, Alan, Parkin, Mark C, Dawe, Gemma, Rabiner, Eugenii A, Gunn, Roger N, Lightman, Stafford L, Nutt, David J, Lingford-Hughes, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169731/
https://www.ncbi.nlm.nih.gov/pubmed/29942043
http://dx.doi.org/10.1038/s41380-018-0107-4