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Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals
Addiction has been proposed as a ‘reward deficient’ state, which is compensated for with substance use. There is growing evidence of dysregulation in the opioid system, which plays a key role in reward, underpinning addiction. Low levels of endogenous opioids are implicated in vulnerability for deve...
Autores principales: | Turton, Samuel, Myers, James FM, Mick, Inge, Colasanti, Alessandro, Venkataraman, Ashwin, Durant, Claire, Waldman, Adam, Brailsford, Alan, Parkin, Mark C, Dawe, Gemma, Rabiner, Eugenii A, Gunn, Roger N, Lightman, Stafford L, Nutt, David J, Lingford-Hughes, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169731/ https://www.ncbi.nlm.nih.gov/pubmed/29942043 http://dx.doi.org/10.1038/s41380-018-0107-4 |
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