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TRPS1 regulates estrogen-receptor binding and histone acetylation at enhancers

The chromatin state is finely tuned to regulate function and specificity for transcription factors such as Estrogen-Receptor alpha (ER) which contributes to cell growth in breast cancer. ER transcriptional potential is mediated, in large part, by the specific associated proteins and co-factors that...

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Detalles Bibliográficos
Autores principales: Serandour, A.A, Mohammed, H, Miremadi, A, Mulder, K.W, Carroll, J.S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169732/
https://www.ncbi.nlm.nih.gov/pubmed/29895970
http://dx.doi.org/10.1038/s41388-018-0312-2