Evaluation of Polygenic Risk Models Using Multiple Performance Measures: A Critical Assessment of Discordant Results

PURPOSE: The area under the receiver operating characteristic curve (AUC) is commonly used for evaluating the improvement of polygenic risk models and increasingly assessed together with the net reclassification improvement (NRI) and integrated discrimination improvement (IDI). We evaluated how rese...

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Detalles Bibliográficos
Autores principales: Martens, Forike K., Tonk, Elisa C. M., Janssens, A. Cecile J.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169739/
https://www.ncbi.nlm.nih.gov/pubmed/29895851
http://dx.doi.org/10.1038/s41436-018-0058-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169739/
https://www.ncbi.nlm.nih.gov/pubmed/29895851
http://dx.doi.org/10.1038/s41436-018-0058-9

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