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Evaluation of Polygenic Risk Models Using Multiple Performance Measures: A Critical Assessment of Discordant Results
PURPOSE: The area under the receiver operating characteristic curve (AUC) is commonly used for evaluating the improvement of polygenic risk models and increasingly assessed together with the net reclassification improvement (NRI) and integrated discrimination improvement (IDI). We evaluated how rese...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169739/ https://www.ncbi.nlm.nih.gov/pubmed/29895851 http://dx.doi.org/10.1038/s41436-018-0058-9 |