Attenuated Codon Optimality Contributes to Neural-Specific mRNA Decay in Drosophila

Tissue-specific mRNA stability is important for cell fate and physiology, but the mechanisms involved are not fully understood. We found that zygotic mRNA stability in Drosophila correlates with codon content: optimal codons are enriched in stable transcripts associated with metabolic functions like...

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Detalles Bibliográficos
Autores principales: Burrow, Dana A., Martin, Sophic, Quail, Jade F., Alhusaini, Najwa, coller, Jeff, Cleary, Micheal D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169788/
https://www.ncbi.nlm.nih.gov/pubmed/30110627
http://dx.doi.org/10.1016/j.celrep.2018.07.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169788/
https://www.ncbi.nlm.nih.gov/pubmed/30110627
http://dx.doi.org/10.1016/j.celrep.2018.07.039

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