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Attenuated Codon Optimality Contributes to Neural-Specific mRNA Decay in Drosophila
Tissue-specific mRNA stability is important for cell fate and physiology, but the mechanisms involved are not fully understood. We found that zygotic mRNA stability in Drosophila correlates with codon content: optimal codons are enriched in stable transcripts associated with metabolic functions like...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169788/ https://www.ncbi.nlm.nih.gov/pubmed/30110627 http://dx.doi.org/10.1016/j.celrep.2018.07.039 |