DNA polymerase ε-dependent modulation of the pausing property of the CMG helicase at the barrier

The proper pausing of replication forks at barriers on chromosomes is important for genome integrity. However, the detailed mechanism underlying this process has not been well elucidated. Here, we successfully reconstituted fork-pausing reactions from purified yeast proteins on templates that had bi...

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Detalles Bibliográficos
Autores principales: Hizume, Kohji, Endo, Shizuko, Muramatsu, Sachiko, Kobayashi, Takehiko, Araki, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169835/
https://www.ncbi.nlm.nih.gov/pubmed/30232092
http://dx.doi.org/10.1101/gad.317073.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169835/
https://www.ncbi.nlm.nih.gov/pubmed/30232092
http://dx.doi.org/10.1101/gad.317073.118

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