Cargando…
DNA polymerase ε-dependent modulation of the pausing property of the CMG helicase at the barrier
The proper pausing of replication forks at barriers on chromosomes is important for genome integrity. However, the detailed mechanism underlying this process has not been well elucidated. Here, we successfully reconstituted fork-pausing reactions from purified yeast proteins on templates that had bi...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169835/ https://www.ncbi.nlm.nih.gov/pubmed/30232092 http://dx.doi.org/10.1101/gad.317073.118 |