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Single-cell RNA-sequencing reveals the existence of naive and primed pluripotency in pre-implantation rhesus monkey embryos

Naive pluripotency exists in epiblast cells of mouse pre-implantation embryos. However, whether the naive pluripotency is transient or nonexistent in primate embryos remains unclear. Using RNA-seq in single blastomeres from 16-cell embryos through to hatched blastocysts of rhesus monkey, we construc...

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Detalles Bibliográficos
Autores principales: Liu, Denghui, Wang, Xinyi, He, Dajian, Sun, Chunli, He, Xiechao, Yan, Lanzhen, Li, Yizhou, Han, Jing-Dong J., Zheng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169889/
https://www.ncbi.nlm.nih.gov/pubmed/30154223
http://dx.doi.org/10.1101/gr.233437.117