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Transcriptional fates of human-specific segmental duplications in brain

Despite the importance of duplicate genes for evolutionary adaptation, accurate gene annotation is often incomplete, incorrect, or lacking in regions of segmental duplication. We developed an approach combining long-read sequencing and hybridization capture to yield full-length transcript informatio...

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Detalles Bibliográficos
Autores principales: Dougherty, Max L., Underwood, Jason G., Nelson, Bradley J., Tseng, Elizabeth, Munson, Katherine M., Penn, Osnat, Nowakowski, Tomasz J., Pollen, Alex A., Eichler, Evan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169893/
https://www.ncbi.nlm.nih.gov/pubmed/30228200
http://dx.doi.org/10.1101/gr.237610.118