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Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes

Polycomb group (PcG) proteins are transcriptional repressors that play important roles in regulating gene expression during animal development. In vitro experiments have shown that PcG protein complexes can compact chromatin to limit the activity of chromatin remodeling enzymes and access of the tra...

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Detalles Bibliográficos
Autores principales: King, Hamish W., Fursova, Nadezda A., Blackledge, Neil P., Klose, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169895/
https://www.ncbi.nlm.nih.gov/pubmed/30154222
http://dx.doi.org/10.1101/gr.237180.118