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Telomere shortening in breast cancer cells (MCF7) under treatment with low doses of the benzylisoquinoline alkaloid chelidonine

Telomeres, the specialized dynamic structures at chromosome ends, regularly shrink with every replication. Thus, they function as an internal molecular clock counting down the number of cell divisions. However, most cancer cells escape this limitation by activating telomerase, which can maintain tel...

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Detalles Bibliográficos
Autores principales: Kazemi Noureini, Sakineh, Fatemi, Leili, Wink, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169906/
https://www.ncbi.nlm.nih.gov/pubmed/30281650
http://dx.doi.org/10.1371/journal.pone.0204901