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Whole-exome sequencing capture kit biases yield false negative mutation calls in TCGA cohorts
The Cancer Genome Atlas (TCGA) provides a genetic characterization of more than ten thousand tumors, enabling the discovery of novel driver mutations, molecular subtypes, and enticing drug targets across many histologies. Here we investigated why some mutations are common in particular cancer types...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169918/ https://www.ncbi.nlm.nih.gov/pubmed/30281678 http://dx.doi.org/10.1371/journal.pone.0204912 |