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Anti-parasitic effect of vitamin C alone and in combination with benznidazole against Trypanosoma cruzi

BACKGROUND: Drugs currently used for the treatment of Chagas’ disease, nifurtimox and benznidazole, have a limited effectiveness and toxic side effects. With the aim of finding new therapeutic approaches, in vitro and in vivo anti-Trypanosoma cruzi activity of vitamin C alone and combined with benzn...

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Detalles Bibliográficos
Autores principales: Puente, Vanesa, Demaria, Agostina, Frank, Fernanda M., Batlle, Alcira, Lombardo, Maria Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169970/
https://www.ncbi.nlm.nih.gov/pubmed/30240395
http://dx.doi.org/10.1371/journal.pntd.0006764