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Maternal hematopoietic TNF, via milk chemokines, programs hippocampal development and memory

TNF is a proinflammatory cytokine with established roles in host defense and immune system organogenesis. Here we report a novel physiological function of TNF that extends its effect beyond the host into the developing offspring. A partial/complete maternal TNF-deficit, specifically in hematopoietic...

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Detalles Bibliográficos
Autores principales: Liu, Bingfang, Zupan, Bojana, Laird, Emma, Klein, Shifra, Gleason, Georgia, Bozinoski, Marjan, Gal, Judit, Toth, Miklos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169993/
https://www.ncbi.nlm.nih.gov/pubmed/24292233
http://dx.doi.org/10.1038/nn.3596