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Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker K(+) channel

Membrane potential regulates the activity of voltage-dependent ion channels via specialized voltage-sensing modules but the mechanisms involved in coupling voltage-sensor movement to pore opening remain unclear due to lack of resting state structures and robust methods to identify allosteric pathway...

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Detalles Bibliográficos
Autores principales:	Fernández-Mariño, Ana I., Harpole, Tyler, Oelstrom, Kevin, Delemotte, Lucie, Chanda, Baron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170002/ https://www.ncbi.nlm.nih.gov/pubmed/29581567 http://dx.doi.org/10.1038/s41594-018-0047-3

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