Cell circuits between B cell progenitors and IL-7(+) mesenchymal progenitor cells control B cell development

B cell progenitors require paracrine signals such as interleukin-7 (IL-7) provided by bone marrow stromal cells for proliferation and survival. Yet, how B cells regulate access to these signals in vivo remains unclear. Here we show that proB and IL-7(+) cells form a cell circuit wired by IL-7R signa...

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Detalles Bibliográficos
Autores principales: Fistonich, Chris, Zehentmeier, Sandra, Bednarski, Jeffrey J., Miao, Runfeng, Schjerven, Hilde, Sleckman, Barry P., Pereira, João P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170173/
https://www.ncbi.nlm.nih.gov/pubmed/30158115
http://dx.doi.org/10.1084/jem.20180778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170173/
https://www.ncbi.nlm.nih.gov/pubmed/30158115
http://dx.doi.org/10.1084/jem.20180778

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