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Piezo1 and G(q)/G(11) promote endothelial inflammation depending on flow pattern and integrin activation

The vascular endothelium is constantly exposed to mechanical forces, including fluid shear stress exerted by the flowing blood. Endothelial cells can sense different flow patterns and convert the mechanical signal of laminar flow into atheroprotective signals, including eNOS activation, whereas dist...

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Detalles Bibliográficos
Autores principales: Albarrán-Juárez, Julián, Iring, Andras, Wang, ShengPeng, Joseph, Sayali, Grimm, Myriam, Strilic, Boris, Wettschureck, Nina, Althoff, Till F., Offermanns, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170174/
https://www.ncbi.nlm.nih.gov/pubmed/30194266
http://dx.doi.org/10.1084/jem.20180483